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This reduction was generally consistent across study subgroups based on baseline characteristics or medications.
The ATHENA trial, which involved 4,628 patients with AF or AFL and more than 2,300 patients receiving Multaq on top of standard therapy, demonstrated a 24% reduction in time to first CV hospitalization or all-cause mortality (P<0. In a placebo-controlled study in patients with severe heart failure requiring recent hospitalization or referral to a specialized heart failure clinic for worsening symptoms (the ANDROMEDA study), patients given dronedarone had a greater than two-fold increase in mortality.sanofi-aventis. phentermine at save generics
To ensure the use of Multaq in the appropriate patient population, sanofi-aventis U. phentermine at save generics In a placebo-controlled study in patients with severe heart failure requiring recent hospitalization or referral to a specialized heart failure clinic for worsening symptoms (the ANDROMEDA study), patients given dronedarone had a greater than two-fold increase in mortality. cialis wmv
The risk mitigation program consists of a Communication Plan for HCPs, a medication guide for patients and post-marketing surveillance.
About dronedarone (Multaq)
Multaq, discovered and developed by sanofi-aventis, is one of the major therapeutic innovations in patients with atrial fibrillation in the last twenty years.027].S. phentermine at save generics The FDA approval is based on five international, multi-center, randomized clinical trials involving nearly 6,300 patients. This reduction was generally consistent across study subgroups based on baseline characteristics or medications. phentermine at save generics Associated cardiovascular risk factors include age over 70 years, hypertension, diabetes, prior cerebrovascular accident, left atrial diameter greater than or equal to 50 mm or left ventricular ejection fraction [LVEF] <40%.
Hypokalemia and hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. cialis 2005
This reduction was generally consistent across study subgroups based on baseline characteristics or medications."
Multaq is to be given twice daily as a 400 mg tablet and should be taken as one tablet with the morning and evening meals.S. phentermine at save generics S.
About sanofi-aventis
Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. phentermine at save generics The patients enrolled in ANDROMEDA had relatively severe heart failure and had been hospitalized, or referred to a specialty heart failure clinic for worsening symptoms.
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