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Patients with atrial fibrillation (AF) or atrial flutter (AFL) soon will have a new treatment option to help improve current management of their disease. This trial showed that Multaq (dronedarone) 400 mg BID, in addition to standard therapy, reduced the combined endpoint of cardiovascular hospitalization or death from any cause by 24% (p<0. To ensure the use of Multaq in the appropriate patient population, sanofi-aventis U. The ANDROMEDA study, was terminated prematurely after enrolment of 627 of 1000 planned patients with congestive heart failure, in relation to excess mortality due to worsening heart failure in the dronedarone group [n=25 versus 12 (placebo), p=0. The elevation has a rapid onset, reaches a plateau after 7 days and is reversible after discontinuation. ducation sp cialis e gen ve " The incidence of atrial fibrillation is growing worldwide in relation to aging populations. ducation sp cialis e gen ve PARIS, July 02, 2009 /PRNewswire-FirstCall/ --Sanofi-aventis announced today that the U.027]. drug interactions xanax amoxicillin

Initiation of Multaq treatment is contraindicated in patients with severe heart failure (NYHA class IV) or NYHA Class II - III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic.S." Multaq is to be given twice daily as a 400 mg tablet and should be taken as one tablet with the morning and evening meals. The ATHENA trial, which involved 4,628 patients with AF or AFL and more than 2,300 patients receiving Multaq on top of standard therapy, demonstrated a 24% reduction in time to first CV hospitalization or all-cause mortality (P<0. ducation sp cialis e gen ve " The landmark ATHENA trial evaluated the efficacy and safety of Multaq in patients with AF/AFL or a recent history of these conditions (71% of these patients had no heart failure, 29% were in NYHA class I-III with stable heart failure). "We are pleased that the FDA has granted approval of Multaq for patients in a therapeutic area that has seen few new treatment options in the last twenty years," said Marc Cluzel, MD, Senior Vice President, Research and Development, sanofi-aventis. ducation sp cialis e gen ve S. In contrast, in ATHENA, all patients had a history of AF/AFL, and 71% of patients had no heart failure, 25% were NYHA class I or II, and only 4% were class III. order xanax with no prescription

This trial showed that Multaq (dronedarone) 400 mg BID, in addition to standard therapy, reduced the combined endpoint of cardiovascular hospitalization or death from any cause by 24% (p<0. "Sanofi-aventis’ commitment to research and development in this area is rewarded today, and we hope it will benefit many patients suffering from this disease. The ANDROMEDA and ATHENA trials were published in the New England Journal of Medicine (NEJM) respectively in 2008 and 2009.1mg/dL following Multaq treatment initiation. ducation sp cialis e gen ve Viehbacher, Chief Executive Officer of sanofi-aventis. ducation sp cialis e gen ve A registration dossier of Multaq is also under regulatory review by the European Medicines Agency (EMEA).001) compared with placebo meeting the primary endpoint.