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Patients with atrial fibrillation (AF) or atrial flutter (AFL) soon will have a new treatment option to help improve current management of their disease.S.
"It is exciting that Multaq will now be available as a treatment option for patients with paroxysmal or persistent atrial fibrillation or atrial flutter," said Stuart Connolly, M.
A registration dossier of Multaq is also under regulatory review by the European Medicines Agency (EMEA).
About sanofi-aventis
Sanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. tramadol hydrochloride tablets label
Multaq should not be coadministered with strong CYP 3A inhibitors or medicinal products that prolong the QT interval. tramadol hydrochloride tablets label LLC also announced the launch of mPACT(TM) - Multaq Partnership for Appropriate Care and Treatment - the Risk Evaluation and Mitigation Strategy (REMS) developed by sanofi-aventis U. Potassium levels should be maintained in the normal range pre and during administration. levitra written on couch
Viehbacher, Chief Executive Officer of sanofi-aventis.S.
The ATHENA trial, which involved 4,628 patients with AF or AFL and more than 2,300 patients receiving Multaq on top of standard therapy, demonstrated a 24% reduction in time to first CV hospitalization or all-cause mortality (P<0. In a placebo-controlled study in patients with severe heart failure requiring recent hospitalization or referral to a specialized heart failure clinic for worsening symptoms (the ANDROMEDA study), patients given dronedarone had a greater than two-fold increase in mortality. tramadol hydrochloride tablets label "
Multaq is to be given twice daily as a 400 mg tablet and should be taken as one tablet with the morning and evening meals.
The ANDROMEDA study, was terminated prematurely after enrolment of 627 of 1000 planned patients with congestive heart failure, in relation to excess mortality due to worsening heart failure in the dronedarone group [n=25 versus 12 (placebo), p=0. tramadol hydrochloride tablets label "Sanofi-aventis’ commitment to research and development in this area is rewarded today, and we hope it will benefit many patients suffering from this disease. Potassium levels should be maintained in the normal range pre and during administration. xanax for treatment of hair pulling
The mPACT(TM) Partnership was developed to assist healthcare professionals (HCPs) with the identification of appropriate patients and to ensure the safe use of Multaq while minimizing risk.5 million people in the European Union. "Based on clinical studies, Multaq reduces the risk of cardiovascular hospitalizations in patients with atrial fibrillation / atrial flutter, this outcome could change the way we approach the management of the disease.
The ANDROMEDA study, was terminated prematurely after enrolment of 627 of 1000 planned patients with congestive heart failure, in relation to excess mortality due to worsening heart failure in the dronedarone group [n=25 versus 12 (placebo), p=0. tramadol hydrochloride tablets label
Important Safety Information
Multaq is contraindicated in patients with NYHA Class IV heart failure or NYHA Class II-III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic. tramadol hydrochloride tablets label , Professor of Medicine & Director, Division of Cardiology, McMaster University, Hamilton, Canada, and co-principal investigator in the ATHENA study.
A registration dossier of Multaq is also under regulatory review by the European Medicines Agency (EMEA).
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