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" The landmark ATHENA trial evaluated the efficacy and safety of Multaq in patients with AF/AFL or a recent history of these conditions (71% of these patients had no heart failure, 29% were in NYHA class I-III with stable heart failure). This unstable population corresponds to the population of the ANDROMEDA trial in which patients receiving dronedarone had a greater than 2-fold increase in mortality compared to placebo. The ATHENA and ANDROMEDA trials provided two sets of data supporting the assessment of the product's benefit risk ratio in two significantly different patient populations. In a placebo-controlled study in patients with severe heart failure requiring recent hospitalization or referral to a specialized heart failure clinic for worsening symptoms (the ANDROMEDA study), patients given dronedarone had a greater than two-fold increase in mortality. diazepam valium sales Multaq is an anti-arrhythmic indicated to reduce the risk of cardiovascular hospitalization in patients with paroxysmal or persistent atrial fibrillation (AF) or atrial flutter (AFL), with a recent episode of AF/AFL and associated cardiovascular risk factors, who are in sinus rhythm or who will be cardioverted.S. diazepam valium sales The ANDROMEDA study, was terminated prematurely after enrolment of 627 of 1000 planned patients with congestive heart failure, in relation to excess mortality due to worsening heart failure in the dronedarone group [n=25 versus 12 (placebo), p=0. soma controlled substance

Most common adverse reactions are diarrhea, nausea, vomiting, abdominal pain, asthenia (weakness) and cutaneous rash. Sanofi-aventis is listed in Paris and in New York . Atrial fibrillation is a potentially life-threatening condition, with significant burden on patients, health care providers and payers. Multaq should not be given to patients who are or may become pregnant (Category X) or nursing.001) when compared to placebo, meeting the study's primary endpoint. diazepam valium sales Food and Drug Administration (FDA) has approved Multaq (dronedarone) 400 mg Tablets. To ensure the use of Multaq in the appropriate patient population, sanofi-aventis U. diazepam valium sales Atrial fibrillation is a potentially life-threatening condition, with significant burden on patients, health care providers and payers. webplus aopis org xanax

Multaq is an anti-arrhythmic indicated to reduce the risk of cardiovascular hospitalization in patients with paroxysmal or persistent atrial fibrillation (AF) or atrial flutter (AFL), with a recent episode of AF/AFL and associated cardiovascular risk factors, who are in sinus rhythm or who will be cardioverted. Associated cardiovascular risk factors include age over 70 years, hypertension, diabetes, prior cerebrovascular accident, left atrial diameter greater than or equal to 50 mm or left ventricular ejection fraction [LVEF] <40%. Atrial flutter, another type of arrhythmia generating in the atrium, occurs less frequently, and may evolve into atrial fibrillation. diazepam valium sales The risk mitigation program consists of a Communication Plan for HCPs, a medication guide for patients and post-marketing surveillance. Hypokalemia and hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. diazepam valium sales S.sanofi-aventis.